Author

Nathan Bouk

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Genomics· 2

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 4 Research Focus:database / resource· 2 Approach:experimental assay· 2 Research Focus:genome assembly· 2 Organism:human· 2 Organism:multiple species· 2 Approach:statistical model· 2 Approach:benchmark study· 1

Frequent Co-Authors

Kim D. PruittiD· 3 shared Eyal Mozes· 2 shared Françoise Thibaud-Nissen· 2 shared Karyn Meltz Steinberg· 2 shared Sean McGrath· 2 shared Terence D. MurphyiD· 2 shared Tina Graves Lindsay· 2 shared Valérie SchneideriD· 2 shared

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2016-2024 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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3 shared papersGenomics

Kim D. PruittORCID

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Author profile →

4 papers

Recent·Most cited

Rapid and sensitive detection of genome contamination at scale with FCS-GX

Alexander Astashyn, Eric S. Tvedte, Deacon Sweeney, Victor Sapojnikov, Nathan Bouk, Victor Joukov, Eyal Mozes, Pooja K Strope, Pape M. Sylla, Lukas Wagner, Shelby L. Bidwell, Larissa C. Brown, Karen Clark, Emily W. Davis, Brian J. Smith-White, , Terence D. Murphy

FCS-GX, a hashed k-mer cross-species aligner with a 709 Gbp curated database, screens most genomes in 0.1-10 minutes and flagged 36.8 Gbp of contamination in GenBank.

Genome biology · Feb 26, 2024Peer-reviewedBioinformatics✦ In-depth digest

Interactive visualization of whole eukaryote genome alignments using NCBI's Comparative Genome Viewer (CGV)

Sanjida H Rangwala, Dmitry Rudnev, Victor Ananiev, Andrea Asztalos, Barrett Benica, Evgeny A. Borodin, Nathan Bouk, Vladislav I. Evgeniev, Vamsi K. Kodali, Vadim Lotov, Eyal Mozes, Dong‐Ha Oh, Marina V. Omelchenko, Sofya Savkina, Ekaterina Sukharnikov, , Valérie Schneider

The paper introduces a new visualization tool, CGV, for analyzing whole genome alignments across species, enabling exploration of structural differences and gene annotations.

bioRxiv · Oct 30, 2023 · PreprintGenomics

Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

Valerie A Schneider, Tina Graves Lindsay, Kerstin Howe, Nathan Bouk, Hsiu-Chuan Chen, Paul A. Kitts, Terence D Murphy, Kim D. Pruitt, Françoise Thibaud-Nissen, Derek Albracht, Robert S Fulton, Milinn Kremitzki, Vince Magrini, Chris Markovic, Sean McGrath, , Deanna M Church

This paper evaluates GRCh38 and de novo haploid assemblies, finding that GRCh38 remains superior for complex genomic regions and coding sequences despite improvements in newer assemblies.

Genome Research · Apr 10, 2017Peer-reviewedGenomics

High-Quality Assembly of an Individual of Yoruban Descent

Karyn Meltz Steinberg, Tina Graves Lindsay, Valerie A. Schneider, Mark J.P. Chaisson, Chad Tomlinson, John Huddleston, Patrick Minx, Milinn Kremitzki, Derek Albrecht, Vincent Magrini, Sean McGrath, Archana Raja, Carl Baker, Lana Harshman, LaDeana W. Hillier, , Richard K. Wilson

This paper presents a high-quality de novo assembly of a Yoruban individual using multiple sequencing technologies and demonstrates the utility of diploid assembly in improving genome quality.

bioRxiv · Aug 2, 2016 · PreprintBioinformatics