Author

Nathan Phan

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 3 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:protein structure· 3 Research Focus:drug response / drug discovery· 2 Approach:Bayesian inference· 1 Approach:deep learning· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Blaise R. KimmeliD· 3 shared Joe Bailey· 2 shared Soren C. Spina· 2 shared Aditya M. KunjapuriD· 1 shared Andrew Hu· 1 shared Gowrish RajagopaliD· 1 shared Grant Walter· 1 shared Joel A. PaulsoniD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

Blaise R. KimmelORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Experimentally Tuned Protein-RNA Rosetta Score Function using Bayesian Optimization

Joe Bailey, Nathan Phan, Soren C. Spina, Rachel B. Getman, Joel A. Paulson, Blaise R. Kimmel

The paper develops an experimentally tuned protein-RNA score function for ROSETTA using Bayesian Optimization to improve energetic agreement with experimental data.

bioRxiv · Jul 20, 2026 · PreprintBioengineering

CovSite: A High-Throughput Blind Covalent Screening Framework for Reactive Site Detection

Andrew Hu, Joe Bailey, Soren C. Spina, Gowrish Rajagopal, Nathan Phan, Blaise R. Kimmel

CovSite identifies reactive protein sites for covalent inhibitors using only structure and electrophile SMILES, achieving high accuracy and throughput.

bioRxiv · Jul 20, 2026 · PreprintBioengineering

Air-driven aldehyde synthesis in engineered bacteria via gene deletion and aryl-alcohol oxidase profiling

Roman M. Dickey, Joshua Bryan, Vishal Somasundaram, Shelby R. Anderson, Nathan Phan, Aditya M. Kunjapur

This paper engineers Escherichia coli to oxidize non-native alcohols using high-expression aryl-alcohol oxidases, enabling air-driven aldehyde synthesis.

bioRxiv · Jul 13, 2026 · PreprintSynthetic Biology

Modular Nanobody Conjugates with Controlled Topology Using Genetically Encoded Non-canonical Amino Acids

Roman Adomanis, Nathan Phan, Grant Walter, Blaise R. Kimmel

This paper introduces a method to create bispecific nanobody conjugates with controlled topology using non-canonical amino acids, enabling precise domain orientation for immune checkpoint blockade therapy.

bioRxiv · Nov 27, 2025 · PreprintBioengineering