Lysine Crotonylation Acts as an Epigenetic Switch for Glutamate Neurotransmission and Spatial Memory
Utsav Mukherjee, Budhaditya Basu, Pratyush S. Suryavanshi, Stacy E. Beyer, Saaman Ghodsi, Nathan Robillard, Yann S. Vanrobaeys, Eric B. Taylor, Joseph Glykys, Ted G. Abel, Snehajyoti Chatterjee
This study identifies lysine crotonylation (Kcr) as an epigenetic regulator of long-term memory and glutamatergic neurotransmission, showing its role in gene expression and synaptic function.
Proceedings of the National Academy of Sciences · Oct 28, 2026Peer-reviewedNeuroscience