Author

Nicholas Ryan

Vanderbilt University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:rat· 1

Frequent Co-Authors

Amanda J. LeaiD· 3 shared Audrey M. ArneriD· 2 shared Grace Rodenberg· 2 shared Alex R. DeCasieniD· 1 shared Amanda D. MeliniD· 1 shared Angelina V. Ruiz-LambidesiD· 1 shared Armando Burgos-RodrigueziD· 1 shared Ashlee GreenieriD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersGenomics

Amanda J. LeaORCID

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3 papers

Recent·Most cited

Early and current environments exert distinct effects on immune function in the Orang Asli

Layla Brassington, Audrey M. Arner, Grace Rodenberg, Nicholas Ryan, Diane Song, Tan Bee Ting A P Tan Boon Huat, Virginia B. Kraus, Janet L. Huebner, Izandis bin Mohd Sayed, Yvonne AL Lim, Vivek V. Venkataraman, Ian J. Wallace, Thomas S. Kraft, Amanda J. Lea

The paper examines how early-life and current environments affect immune function in the Orang Asli, finding current lifestyle has stronger effects on immune gene expression than early-life conditions.

bioRxiv · Jul 30, 2026 · PreprintGenetics

Age and early life adversity shape heterogeneity of the epigenome across tissues in macaques

Baptiste Sadoughi, Rachel M. Petersen, Sam K. Patterson, Beth Slikas, Christine Adjangba, Nicholas Ryan, Christina E. Costa, Laura E. Newman, Marina M. Watowich, Cameron R. Kelsey, Ashlee Greenier, Elisabeth A. Goldman, Josué E. Negrón-Del Valle, Daniel Phillips, Indya Thompson, , Jérôme Sallet

The paper shows that age and early life adversity affect DNA methylation across tissues in macaques, with distinct but overlapping patterns.

Science · Jun 18, 2026Peer-reviewedGenomics

Public RNA-seq data are not representative of global human diversity

Irene Gallego Romero, Grace Rodenberg, Audrey M. Arner, Ling Li, Isobel J. Beasley, Ryan Rossow, Nicholas Ryan, Selina Wang, Amanda J. Lea

The paper analyzes RNA-seq data from public databases and finds significant underrepresentation of non-European populations, highlighting biases in population descriptors.

bioRxiv · Oct 11, 2024 · PreprintGenomics