Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder
Nick Green, Hongyu Gao, Xiaona Chu, Qiuyue Yuan, Patrick C. McGuire, Dongbing Lai, Guanglong Jiang, Xiaoling Xuei, Jill L. Reiter, Julia Stevens, Greg Trevor Sutherland, Alison Goate, Zhiping P. Pang, Paul A. Slesinger, Ronald P. Hart, , Yunlong Liu
The paper uses multiomic profiling of the caudate nucleus to identify gene expression and chromatin changes in AUD, linking them to risk genes through QTL analysis.
bioRxiv · Aug 2, 2024 · PreprintNeuroscience