Alpha hemolysin polymorphisms in methicillin-resistant Staphylococcus aureus clinical isolates regulate ADAM10-dependent neutrophil IL-1 beta secretion
Karl Liboro, Jolynn Tran Chau, James D Begando, Serena Abbondante, Angela Lackner, Yan Sun, Michaela Ellen Marshall, Nikitina Ly, Victor D. Johnson, George Dubyak, Michael S. Gilmore, Reginald McNulty, Camille André, Eric M. Pearlman
The paper shows that Hla polymorphisms in MRSA strains affect ADAM10-dependent neutrophil IL-1β secretion and corneal disease severity.
bioRxiv · Dec 14, 2025 · PreprintMicrobiology