Molecular diversity and lineage commitment of human interneuron progenitors
Dmitry Velmeshev, Manideep Chavali, Tomasz Jan Nowakowski, Mohini Bhade, Simone Mayer, Nitasha Goyal, Beatriz Alvarado, Walter Mancia, Shaohui Wang, Matthew L Speir, Maximilian Haeussler, David H. Rowitch, Arturo Álvarez-Buylla, Eric Jinsheng Huang, Mercedes F. Paredes, Arnold R. Kriegstein
The paper identifies molecular subtypes of human interneuron progenitors and immature interneurons using single-cell RNA sequencing and compares them to mouse data, revealing species-specific gene programs.
bioRxiv · May 13, 2021 · PreprintNeuroscience