Author

Nivedhitha Devaraju

Manipal Academy of Higher Education

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genomics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anila GeorgeiD· 2 shared Aswin Anand PaiiD· 2 shared Gokulnath MahalingamiD· 2 shared K. Manjunatha PrasadiD· 2 shared Kumarasamypet Murugesan MohankumariD· 2 shared Nithin Sam RaviiD· 2 shared Poonkuzhali BalasubramanianiD· 2 shared Ryo Kurita· 2 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Anila GeorgeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Precise modelling and correction of a spectrum of β-thalassemic mutations in human erythroid cells by base editors

K. Manjunatha Prasad, Nivedhitha Devaraju, Anila George, Nithin Sam Ravi, Gokulnath Mahalingam, Vignesh Rajendiran, Lokesh Panigrahi, Vigneshwaran Venkatesan, Kartik Lakhotiya, Yogapriya Moorthy, Aswin Anand Pai, Yukio Nakamura, Ryo Kurita, Poonkuzhali Balasubramanian, Saravanabhavan Thangavel, , Kumarasamypet Murugesan Mohankumar

This study demonstrates the use of base editors to precisely correct various β-thalassemic mutations in human erythroid cells, showing efficient and scarless mutation correction with normal hemoglobin variants.

bioRxiv · Jun 1, 2022 · PreprintGenomics

Identification of novel HPFH-like mutations by CRISPR base editing that elevates the expression of fetal hemoglobin

Nithin Sam Ravi, Beeke Wienert, Stacia K. Wyman, Henry William Bell, Anila George, Gokulnath Mahalingam, Jonathan T. Vu, K. Manjunatha Prasad, Bhanu Prasad Bandlamudi, Nivedhitha Devaraju, Vignesh Rajendiran, Nazar Syedbasha, Aswin Anand Pai, Yukio Nakamura, Ryo Kurita, , Kumarasamypet Murugesan Mohankumar

This study uses CRISPR base editing to identify novel mutations in the HBG promoter that increase fetal hemoglobin expression without harmful effects.

eLife · Feb 11, 2022Peer-reviewedGenomics