Chemokine Signaling Shapes Hepatic Lipid Homeostasis through the CXCL12/CXCR4/CXCR7 Axis
Rachel Barkan-Michaeli, Chaim Atay Fainshtein, Hadar Bar-Dagan, Nof Hadar, Einat Cinnamon, Ilan Stein, Kfir Sharabi
This study identifies the CXCL12/CXCR4/CXCR7 axis as a regulator of hepatic lipid homeostasis, showing CXCR7's role in lipid accumulation and suggesting it as a therapeutic target for metabolic liver disease.
bioRxiv · Jun 10, 2026 · PreprintPhysiology