O. E. Burata

Peripheral mutations underlie promiscuous transport of quaternary ammonium antiseptics by Small Multidrug Resistance transporters

The paper identifies peripheral mutations that enable promiscuous transport of quaternary ammonium antiseptics by SMR transporters, revealing that substrate preference changes through mutations outside the binding pocket.

Lysosome transporter purification and reconstitution identifies Ypq1 as a pH-gated lysine transporter

The paper develops a method to overexpress, purify, and reconstitute the lysine transporter Ypq1 in yeast vacuoles, demonstrating its pH-gated transport function and lysine-dependent stability.

Crystal structures of bacterial Small Multidrug Resistance transporter EmrE in complex with structurally diverse substrates

The paper determines crystal structures of EmrE, a bacterial SMR transporter, in complex with various substrates, revealing structural flexibility in the binding site.