Author

O. Melanker

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Evolutionary Biology· 1

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

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G. Schreiber· 1 shared P. A. Goloubinoff· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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1 shared paperEvolutionary Biology

G. Schreiber

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1 paper

Recent·Most cited

In vitro evolution of uracil glycosylase towards DnaKJ and GroEL binding evolves different misfolded states

O. Melanker, P. A. Goloubinoff, G. Schreiber

This study uses in vitro evolution to select uracil glycosylase mutants binding to GroEL, DnaKJ, or E. coli extract, revealing distinct misfolded states and selection pressures.

bioRxiv · Nov 30, 2021Evolutionary Biology