Network-driven cancer cell avatars for combination discovery and biomarker identification for DNA Damage Response inhibitors
O. Papp, V. Jordan, S. Hetey, R. Balazs, A. Bartha, N. N. Ordasi, S. Kamp, B. Farkas, J. Mettetal, J. R. Dry, D. Young, D. Veres, B. Sidders, K. C. Bulusu
The paper introduces a network biology-driven simulation method to predict effective drug combinations and identify biomarkers for DNA Damage Response inhibitors using cancer cell avatars.
bioRxiv · Nov 20, 2023Cancer Biology