Author

O. Pybus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:virus· 3 Assay:whole-genome sequencing· 3 Research Focus:phylogenetics / evolution· 2 Approach:Bayesian inference· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Rambaut· 2 shared J. McCrone· 2 shared L. du Plessis· 2 shared V. Hill· 2 shared A. Carabelli· 1 shared A. Comas-Garcia· 1 shared A. Herrera-Estrella· 1 shared A. Katzourakis· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersEvolutionary Biology

A. Rambaut

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Comparing the evolutionary dynamics of predominant SARS-CoV-2 virus lineages co-circulating in Mexico

H. G. Castelan-Sanchez, L. Delaye, R. P. Inward, S. Dellicour, B. Gutierrez, N. Martinez de la Vina, C. Boukadida, O. Pybus, G. de Anda Jauregui, P. Guzman, M. Flores Garrido, O. Fontanelli, M. H. Rosales, A. Meneses, G. Olmedo-Alvarez, , M. Escalera-Zamudio

The paper analyzes the evolutionary dynamics of five dominant SARS-CoV-2 lineages in Mexico, showing lineage replacement patterns and regional spread.

bioRxiv · Jul 5, 2022Evolutionary Biology

The origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 in the UK

V. Hill, L. du Plessis, T. P. A. Peacock, D. Aggarwal, A. Carabelli, R. Colquhoun, N. Ellaby, E. Gallagher, N. Groves, B. Jackson, J. McCrone, A. N. O'Toole, A. Price, T. Sanderson, E. Scher, , A. Rambaut

This study investigates the origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 (Alpha) in the UK, finding that a chronically-infected immunocompetent individual likely drove its rapid mutation and spread.

bioRxiv · Mar 8, 2022Evolutionary Biology

Prisoner of War dynamics explains the time-dependent pattern of substitution rates in viruses

M. Ghafari, P. Simmonds, O. Pybus, A. Katzourakis

The paper introduces a mechanistic model explaining time-dependent substitution rate decay in viruses, showing it applies across virus types and revises evolutionary timescales for HCV and sarbecoviruses.

bioRxiv · Feb 9, 2021Evolutionary Biology

A dynamic nomenclature proposal for SARS-CoV-2 to assist genomic epidemiology

A. Rambaut, E. C. Holmes, V. Hill, A. OToole, J. McCrone, C. Ruis, L. du Plessis, O. Pybus

This paper proposes a dynamic nomenclature system for SARS-CoV-2 to improve genomic epidemiology by tracking active lineages and their spread.

bioRxiv · Apr 17, 2020Microbiology