Author

O. Roopnarine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:fluorescence / live-cell microscopy· 1 Assay:proteomics· 1

Frequent Co-Authors

D. D. Thomas· 2 shared A. R. Thompson· 1 shared C. C. Aldrich· 1 shared L. N. Roelike· 1 shared P. A. Bidwell· 1 shared R. L. Cornea· 1 shared R. T. Rebbeck· 1 shared S. L. Yuen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersBiophysics

D. D. Thomas

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2 papers

Recent·Most cited

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

O. Roopnarine, S. L. Yuen, A. R. Thompson, L. N. Roelike, R. T. Rebbeck, P. A. Bidwell, C. C. Aldrich, R. L. Cornea, D. D. Thomas

The paper uses a FRET assay to screen compounds affecting the cardiac SERCA pump, identifying activators and inhibitors with potential therapeutic applications for heart failure.

bioRxiv · Feb 22, 2023 · PreprintBiophysics

Actin-binding compounds that affect the kinetics of the interaction of cardiac myosin with actin

O. Roopnarine, D. D. Thomas

This study examines ten actin-binding compounds' effects on cardiac myosin-actin interaction kinetics, revealing their impact on ATP affinity and potential therapeutic applications for hypertrophic cardiomyopathy.

bioRxiv · Sep 16, 2020Biochemistry