The Phosphorylation State of Melanophilin, a Myosin Va Adapter Protein, Biases the Tug-of-War Between Myosin Va and Kinesin-1 on Liposomes at Actin-Microtubule Intersections In Vitro
Brandon M. Bensel, Patricia M. Fagnant, Jill E. Macfarlane, Oban Galbraith, Kathleen M. Trybus, David M. Warshaw
This study shows phosphorylated melanophilin biases liposome exit from actin-microtubule intersections toward actin, while dephosphorylated melanophilin biases exit toward microtubules.
bioRxiv · Oct 16, 2026 · PreprintBiophysics