Author

Oliver Cope

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aarav MehtaiD· 2 shared Christina Ford· 2 shared Elizabeth BrunkiD· 2 shared Jingting CheniD· 2 shared Yue WangiD· 2 shared Alison M. Rojas· 1 shared Benjamin J. ParkeriD· 1 shared Caroline A Tomblin· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Aarav MehtaORCID

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Author profile →

3 papers

Recent·Most cited

Evolution of endogenized densoviral elements across aphid species

Paula Rozo-López, Joseph Torres, Vanesa Torres, Meaghan J. Adler, Keertana Tallapragada, Oliver Cope, Benjamin J. Parker

The paper studies the evolution of densoviral endogenous elements in aphids, finding lineage-specific variation and evidence for both vertical and horizontal transmission.

bioRxiv · Jul 30, 2026 · PreprintEvolutionary Biology

Extrachromosomal DNA Gives Cancer a New Evolutionary Pathway

Yue Wang, Oliver Cope, Jingting Chen, Aarav Mehta, Dalia Fleifel, Christina Ford, Poorya Behnamie, Molly Murray, Santiago Haase, Saygin Gulec, Logan Slade, Tim C. Elston, Philip M. Spanheimer, Caroline A Tomblin, Alison M. Rojas, , Elizabeth Brunk

The paper shows that ecDNA allows tumors to adapt rapidly by maintaining a spectrum of gene expression levels across cells, rather than relying on clonal expansion.

bioRxiv · Apr 26, 2025 · PreprintGenomics

Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses

Kohen Goble, Aarav Mehta, Damien Guilbaud, Jacob Fessler, Jingting Chen, William Nenad, Christina Ford, Oliver Cope, Darby Cheng, William Dennis, Nithya Gurumurthy, Yue Wang, Kriti Shukla, Elizabeth Brunk

This study introduces an automated pipeline for detecting and quantifying ecDNA in FISH images to analyze drug response mechanisms in cancer cells.

Frontiers in Pharmacology · Feb 3, 2025Peer-reviewedCancer Biology