Author

Kohen Goble

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aarav MehtaiD· 2 shared Christina Ford· 2 shared Elizabeth BrunkiD· 2 shared Jacob Fessler· 2 shared Jingting CheniD· 2 shared Yue WangiD· 2 shared Damien GuilbaudiD· 1 shared Danielle Cannon· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Aarav MehtaORCID

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2 papers

Recent·Most cited

Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses

Kohen Goble, Aarav Mehta, Damien Guilbaud, Jacob Fessler, Jingting Chen, William Nenad, Christina Ford, Oliver Cope, Darby Cheng, William Dennis, Nithya Gurumurthy, Yue Wang, Kriti Shukla, Elizabeth Brunk

This study introduces an automated pipeline for detecting and quantifying ecDNA in FISH images to analyze drug response mechanisms in cancer cells.

Frontiers in Pharmacology · Feb 3, 2025Peer-reviewedCancer Biology

CytoCellDB: A Resource Database For Classification and Analysis of Extrachromosomal DNA in Cancer

Jacob Fessler, Stephanie Ting, Hong Yi, Santiago Haase, Jingting Chen, Saygin Gulec, Yue Wang, Nathan Smyers, Kohen Goble, Danielle Cannon, Aarav Mehta, Christina Ford, Elizabeth Brunk

CytoCellDB is a database that expands the number of cancer cell lines with ecDNA annotations, enabling analysis of ecDNA in relation to molecular data and drug responses.

bioRxiv · Dec 18, 2023 · PreprintGenomics