Dietary fibre combinations modulate gut microbiome composition and metabolic responses in zebrafish, with lasting effects on intestinal barrier gene expression
Justin Abi Assaf, Gwenaelle Le Gall, Ruth Sullivan, Anastasia Bezrucico-Pyatakov, Daniel Clifton, Isaac Harris, Ozlem Pullin, Simone Immler
This study shows that combining apple pectin and cellulose in zebrafish diets leads to non-additive gut microbiome changes and lasting intestinal barrier effects.
bioRxiv · Nov 9, 2026 · PreprintSystems Biology