Bioluminescent zebrafish transplantation model for drug discovery
M. Hason, J. Jovicic, I. Vonkova, M. Bojic, T. Simon-Vermot, R. M. White, P. Bartunek
This study develops a bioluminescent zebrafish model to screen kinase inhibitors for cancer therapy, finding that NanoLuc luciferase enables sensitive and rapid in vivo drug response evaluation.
bioRxiv · Mar 3, 2022Pharmacology & Toxicology