A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome
K. Ahuja, Marjan Vandenabeele, Fatemeharefeh Nami, Evy Lefevere, J. Van hoecke, Steven Bergmans, Marie Claes, Tim Vervliet, Katrien Neyrinck, T. Burg, D. De Herdt, P. Bhaskar, Y. Zhu, Zoe J. Looser, Jens Loncke, , Lies De Groef
This study investigates the role of oligodendroglia in Wolfram syndrome using mouse models and iPSC-derived cells, finding preserved oligodendroglia function and suggesting alternative targets for treatment.
Acta Neuropathologica Communications · Aug 28, 2024Peer-reviewedNeuroscience