CD8 co-receptor enhances T cell activation without any effect on initial attachment
P. Robert, L. Limozin, P. A. van der Merwe, P. Bongrand
This study investigates how CD8 co-receptor affects T cell activation by analyzing TCR-pMHC interactions using single-molecule techniques, finding that CD8 enhances spreading responses rather than initial binding.
bioRxiv · May 5, 2020Immunology