Author

P. Robert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

L. Limozin· 4 shared B. Kerfelec· 2 shared P. A. van der Merwe· 2 shared P. Chames· 2 shared A. Aimard· 1 shared A. Huhn· 1 shared B. Rozycki· 1 shared B. Schwessinger· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersBiophysics

L. Limozin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Decoupling individual host response and immune cell engager cytotoxic potency

C. Gonzalez Gutierrez, A. Aimard, M. Pelicot-Biarnes, B. Kerfelec, P.-H. Puech, P. Robert, F. Piazza, P. Chames, L. Limozin

The paper measures cytotoxicity of bispecific antibodies using NK cells and introduces a model to decouple host response from engager characteristics.

bioRxiv · Jun 22, 2024Biophysics

Mechanical forces impair antigen discrimination by reducing differences in T cell receptor off-rates

J. Pettmann, L. Awada, B. Rozycki, A. Huhn, S. Faour, M. A. Kutuzov, L. Limozin, T. R. Weikl, P. A. van der Merwe, P. Robert, O. Dushek

The paper shows mechanical forces reduce T cell antigen discrimination by accelerating off-rates of higher-affinity antigens.

bioRxiv · May 5, 2022 · PreprintImmunology

CD8 co-receptor enhances T cell activation without any effect on initial attachment

P. Robert, L. Limozin, P. A. van der Merwe, P. Bongrand

This study investigates how CD8 co-receptor affects T cell activation by analyzing TCR-pMHC interactions using single-molecule techniques, finding that CD8 enhances spreading responses rather than initial binding.

bioRxiv · May 5, 2020Immunology

Nanobody-antigen catch-bond reveals NK cell mechanosensitivity

C. Gonzalez, P. Chames, B. Kerfelec, D. Baty, P. Robert, L. Limozin

This study measures antigen-antibody bond behavior under force using nanobodies and flow chamber assays, revealing catch bond properties and NK cell mechanosensitivity.

bioRxiv · Aug 7, 2018 · PreprintBiophysics

A near complete haplotype-phased genome of the dikaryotic wheat stripe rust fungus Puccinia striiformis f. sp. tritici reveals high inter-haplotype diversity

B. Schwessinger, J. Sperschneider, W. Cuddy, M. Miller, D. Garnica, J. Taylor, P. Dodds, M. Figueroa, P. Robert, J. Rathjen

This paper presents a haplotype-phased genome assembly of the wheat stripe rust fungus, revealing high inter-haplotype diversity and novel genomic features associated with virulence.

bioRxiv · Dec 7, 2017Microbiology