SP1 and STAT3 functionally synergize to induce the RhoU small GTPase and a subclass of non-canonical WNT responsive genes correlating with poor prognosis in breast cancer.
E. Monteleone, V. Orecchia, P. Corrieri, D. Schiavone, L. Avalle, E. Moiso, A. Savino, I. Molineris, P. Provero, V. Poli
This study identifies SP1 and STAT3 cooperation in inducing RhoU and non-canonical WNT responsive genes linked to poor breast cancer prognosis.
bioRxiv · Aug 9, 2018Cancer Biology