Core material and surface chemistry of Layer-by-Layer (LbL) nanoparticles independently direct uptake, transport, and trafficking in preclinical blood-brain barrier (BBB) models
N. G. Lamson, A. J. Pickering, J. Wyckoff, P. Ganesh, J. P. Straehla, P. T. Hammond
This study shows that nanoparticle core stiffness and surface chemistry independently affect uptake, transport, and trafficking across the blood-brain barrier in vitro and in vivo.
bioRxiv · Oct 31, 2022 · PreprintBioengineering