The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations
J. Jia, E. Absmeier, N. Holton, A. J. Pietrzyk-Brzezinska, P. Hackert, K. E. Bohnsack, M. T. Bohnsack, M. C. Wahl
The paper examines how somatic cancer mutations in ASCC2 and ASCC3 affect their interaction, reducing affinity and potentially impacting DNA repair.
bioRxiv · May 22, 2020Biochemistry