Topoisomerase 2b induces DNA breaks to regulate human papillomavirus replication
P. Kaminski, S. Hong, T. Kono, P. Hoover, L. A. Laimins
This study shows that TOP2β induces DNA breaks to regulate HPV replication by interacting with CTCF/SMC1 at viral late regions, leading to DNA damage and impaired repair.
bioRxiv · Jan 7, 2021Microbiology