Combining Hypoxia-Activated Prodrugs and Radiotherapy in silico: Impact of Treatment Scheduling and the Intra-Tumoural Oxygen Landscape
S. J. Hamis, M. Kohandel, L. J. Dubois, A. Yaromina, P. Lambin, G. G. Powathil
This paper uses in silico models to show how hypoxia-activated prodrugs and radiotherapy interact, with treatment outcomes depending on scheduling and tumour oxygen levels.
PLOS Computational Biology · Aug 3, 2020Peer-reviewedCancer Biology