Cancer BiologyPLOS Computational BiologyPeer-reviewed
Combining Hypoxia-Activated Prodrugs and Radiotherapy in silico: Impact of Treatment Scheduling and the Intra-Tumoural Oxygen Landscape
S. J. Hamis, M. Kohandel, L. J. Dubois…·G. G. Powathil
This paper uses in silico models to show how hypoxia-activated prodrugs and radiotherapy interact, with treatment outcomes depending on scheduling and tumour oxygen levels.
DOI 10.1371/journal.pcbi.1008041