Combined SPT and FCS methods highlight a mechanism of RNAP II oversampling in cell nuclei
M. FOURNIER, P. LECLERC, A. LERAY, D. CHAMPELOVIER, F. AGBAZAHOU, G. BIDAUX, A. FURLAN, L. HELIOT
The paper combines SPT and FCS to study RNAP II motility, revealing different diffusion states and oversampling of nuclear subdomains, proposing a new model of transcription regulation.
bioRxiv · Jul 27, 2022Biophysics