Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells
S. Miller, P. Coit, E. Gensterblum-Miller, P. Renauer, N. C. Kilian, M. Schonfeld, P.-S. Tsou, A. H. Sawalha
This study identifies hypomethylation of STAT1 and HLA-DRB1 in lupus CD8+ T cells, linking it to type-I interferon-dependent HLA-DRB1 expression and immune activation.
bioRxiv · Aug 22, 2018Immunology