Regression of Human Breast Carcinoma in Nude Mice After Adsflt Gene Therapy is Mediated by Tumor Vascular Endothelial Cell Apoptosis
A. Felici, D. P. Bottaro, A. Mangoni, P. Reusch, D. Marme, I. Kovesdi, D. M. De Silva, Y. H. Lee, M. C. Capogrossi, J. Mühlhauser
This study shows that Adsflt gene therapy reduces tumor volume and vascular density in breast cancer models by inducing vascular endothelial cell apoptosis.
bioRxiv · Jul 19, 2020Cancer Biology