EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition
P. Romero, L. Richart, S. Aflaki…·R. Margueron
This study shows that EZH2 mutations in follicular lymphoma alter H3K27 methylation and transcriptional responses to PRC2 inhibition, with clinical implications for patient stratification.