Enzyme catalysis prior to aromatic residues: reverse engineering of a dephosphoCoA kinase
M. Makarov, J. Meng, V. Tretyachenko, P. Srb, A. Brezinova, V. G. Giacobelli, L. Bednarova, J. Vondrasek, A. K. Dunker, K. Hlouchova
This study shows that enzyme catalysis can occur without aromatic amino acids by testing variants of dephosphoCoA kinase with reduced amino acid alphabets.
bioRxiv · Nov 11, 2020Biochemistry