P. Vesela

Two different phospholipases C, Isc1 and Pgc1, cooperate to regulate mitochondrial function

The paper shows that Isc1 and Pgc1 phospholipases cooperate to regulate mitochondrial function and lipid homeostasis through a feedback loop involving phosphatidylglycerol and diacylglycerol.

Microdomain protein Nce102 is a local sensor of plasma membrane sphingolipid balance

The paper shows Nce102 senses sphingolipid balance at the plasma membrane by redistributing in response to sphingolipid demand and regulating sphingolipid synthesis.

The lipid droplet protein Pgc1 controls the subcellular distribution of phosphatidylglycerol

The paper shows that Pgc1, a phosphatidylglycerol-specific phospholipase, is stored and regulated by lipid droplets to control PG distribution in yeast.