M. Del Poeta

The paper shows Nce102 senses sphingolipid balance at the plasma membrane by redistributing in response to sphingolipid demand and regulating sphingolipid synthesis.

This paper evaluates three vaccination strategies using heat-killed Cryptococcus neoformans Δsgl1 to protect against cryptococcosis in immunocompromised hosts, showing robust protection across preventative, therapeutic, and reactivation models.

This study shows that cholesterol and sphingomyelin in lipid rafts are essential for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages.

This study screens 1,127 compounds against Aspergillus fumigatus, identifies miltefosine as fungicidal, and reveals RmiA as a transcription factor regulating sphingolipid biosynthesis involved in miltefosine resistance.

This study shows that extracellular vesicles from Candida albicans inhibit biofilm formation, yeast-to-hypha differentiation, and virulence by altering gene expression and morphology.

This study identifies how the Rra1 protein in Cryptococcus neoformans internalizes and recycles in response to alkaline pH, enabling the fungus to adapt to the human host environment.

This study shows fenbendazole inhibits Cryptococcus growth in vitro and in mice, reduces virulence, and synergizes with amphotericin B.