Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in 40S small ribosomal subunit
J. Brito Querido, M. Sokabe, I. Diaz-Lopez, Y. Gordiyenko, P. Zuber, Y. Du, L. Albacete-Albacete, V. Ramakrishnan, C. S. Fraser
This study determines the structure of Pdcd4 bound to the 40S ribosomal subunit, revealing its binding site and mechanism in translational control.
bioRxiv · May 1, 2024 · PreprintBiochemistry