Divergent transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1 paralogs
L. MANCEAU, J. RICHARD ALBERT, P.-L. LOLLINI, M. V. C. GREENBERG, P. GILARDI-HEBENSTREIT, V. Ribes
This study compares the transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1, revealing distinct genomic and cellular effects that explain differences in rhabdomyosarcoma manifestations.
bioRxiv · Aug 18, 2021Cancer Biology