Cancer BiologybioRxiv
Divergent transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1 paralogs
L. MANCEAU, J. RICHARD ALBERT, P.-L. LOLLINI…·V. Ribes
This study compares the transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1, revealing distinct genomic and cellular effects that explain differences in rhabdomyosarcoma manifestations.