Polymeric Pathogen-like Particles-Based Combination Adjuvants Elicit Potent Mucosal T Cell Immunity to Influenza A Virus
Brock A Bakke, Randall Toy, Woojong Lee, Pallab Pradhan, Gabriela Vogel, Chandranaik Marinaik, Autumn Larsen, Yoshihiro Kawaoka, Krishnendu A Roy, M Suresh
This study develops PLGA-based pathogen-like particles with TLR agonists that enhance mucosal T cell immunity against influenza A virus when combined with a nanoemulsion adjuvant.
bioRxiv · Jul 10, 2020Immunology