Multiplexed Glycan Immunofluorescence Identification of Pancreatic Cancer Cell Subpopulations in Both Tumor and Blood Samples
Braelyn Binkowski, Zachary L. Klamer, ChongFeng Gao, Ben Staal, Anna Repesh, Hoang-Le Tran, David M. Brass, Pamela Bartlett, Steve Gallinger, Maria Blomqvist, J. Bradley Morrow, Peter J. Allen, Chanjuan Shi, Aatur Dilip Singhi, Randall E. Brand, , Brian B. Haab
This study identifies PDAC cancer cell subpopulations using multiplexed glycan immunofluorescence and shows consistent aberrant glycan signatures in both tumor and blood samples, improving detection beyond CA19-9 alone.
Science Advances · Mar 7, 2025Peer-reviewedCancer Biology