Author

Patrick McConnell

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

James D. DeBrechtiD· 2 shared John A. CooperiD· 2 shared Olivia L. MooreniD· 2 shared Mahapatra Anshuman JaysinghiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

James D. DeBrechtORCID

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2 papers

Recent·Most cited

Biochemical Functions of the Membrane-Binding Domain of CARMIL

Olivia L. Mooren, Patrick McConnell, James D. DeBrecht, John A. Cooper

This study investigates the biochemical functions of the MB domain of CARMIL, showing it targets proteins to membranes, activates CP, and enhances actin assembly.

Journal of Biological Chemistry · Apr 22, 2026Peer-reviewedBiochemistry

Reconstitution of Arp2/3-Nucleated Actin Assembly with CP, V-1 and CARMIL

Olivia L. Mooren, Patrick McConnell, James D. DeBrecht, Mahapatra Anshuman Jaysingh, John A. Cooper

The paper investigates whether CPI-motif proteins activate or inhibit Arp2/3-mediated actin assembly by reconstituting the system with purified components and finds that CARMIL promotes actin assembly by counteracting V-1 inhibition.

Current Biology · Oct 21, 2024Peer-reviewedCell Biology