Author

Olivia L. Mooren

Washington University in St. LouisORCID 0009-0006-4408-9475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

John A. CooperiD· 3 shared James D. DeBrechtiD· 2 shared Patrick McConnell· 2 shared Andrea SorannoiD· 1 shared Chenbo YaniD· 1 shared David SeptiD· 1 shared Dennis GoldfarbiD· 1 shared Emily WilkersoniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

John A. CooperORCID

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3 papers

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedApr 22, 2026

Biochemical Functions of the Membrane-Binding Domain of CARMIL

Olivia L. Mooren, Patrick McConnell, James D. DeBrecht, John A. Cooper

This study investigates the biochemical functions of the MB domain of CARMIL, showing it targets proteins to membranes, activates CP, and enhances actin assembly.

DOI 10.1016/j.jbc.2026.111484

proteomicsexperimental assay

𝕏 PostBluesky

Cell BiologyCurrent BiologyPeer-reviewedOct 21, 2024

Reconstitution of Arp2/3-Nucleated Actin Assembly with CP, V-1 and CARMIL

Olivia L. Mooren, Patrick McConnell, James D. DeBrecht…·John A. Cooper

The paper investigates whether CPI-motif proteins activate or inhibit Arp2/3-mediated actin assembly by reconstituting the system with purified components and finds that CARMIL promotes actin assembly by counteracting V-1 inhibition.

6 citations

experimental assaycell signaling & trafficking

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BiochemistryJournal of Molecular BiologyPeer-reviewedAug 17, 2023

Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein

Olivia L. Mooren, Melissa D. Stuchell‐Brereton, Patrick McConnell…·Andrea Soranno

This study investigates the biophysical mechanism of allosteric regulation of actin capping protein using single-molecule FRET and MD simulations, revealing conformational changes linked to ligand binding.

7 citations

microscopy & imaging analysisstatistical model

𝕏 PostBluesky