Author

Patrick Secrest

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Ajit P VarkiiD· 2 shared Andrea VerhageniD· 2 shared Aniruddha SasmaliD· 2 shared Hai YuiD· 2 shared Naazneen KhaniD· 2 shared Nissi M. VarkiiD· 2 shared Saurabh Srivastava· 2 shared Xi CheniD· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Ajit P VarkiORCID

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Author profile →

3 papers

Recent·Most cited

Increased atherosclerosis and expression of inflammarafts in macrophage foam cells in AIBP-deficient mice

Shenglin Li, Nicolaus Nazarenkov, Elena A. Alekseeva, Soo-Ho Choi, Juliana Maria Navia Pelaez, Aakash V. Patel, Patrick Secrest, Philip L.S.M. Gordts, Sven Heinz, Yury I. Miller

This study shows that AIBP deficiency in mice leads to increased foam cell inflammation and atherosclerosis through enhanced inflammaraft expression and lipid accumulation.

Scientific Reports · Feb 7, 2026Peer-reviewedImmunology

Development and applications of sialoglycan-recognizing probes (SGRPs) with defined specificities: exploring the dynamic mammalian sialoglycome

Saurabh Srivastava, Andrea Verhagen, Aniruddha Sasmal, Brian R. Wasik, Sandra L. Diaz, Hai Yu, Barbara A. Bensing, Naazneen Khan, Zahra Khedri, Patrick Secrest, Paul M. Sullam, Nissi M. Varki, Xi Chen, Colin R. Parrish, Ajit P Varki

The paper develops sialoglycan-recognizing probes (SGRPs) to systematically study mammalian sialoglycome dynamics using established laboratory techniques.

Glycobiology · Aug 4, 2022Peer-reviewedMolecular Biology

Rapid evolution of bacterial AB5 toxin B subunits independent of A subunits: sialic acid binding preferences correlate with host range and toxicity

Naazneen Khan, Aniruddha Sasmal, Zahra Khedri, Patrick Secrest, Andrea Verhagen, Saurabh Srivastava, Nissi M. Varki, Xi Chen, Hai Yu, Travis Beddoe, Adrienne W. Paton, James C. Paton, Ajit P Varki

The paper shows bacterial AB5 toxin B subunits evolve rapidly and independently of A subunits, with sialic acid binding preferences linked to host range and toxicity.

bioRxiv · May 28, 2021 · PreprintMolecular Biology