A new mouse model for a high-risk AMD variant, ARMS2A69S
Navdeep Gogna, Gayle B. Collin, Lillian F. Hyde, Lisa V. Stone, Ravi S. Pandey, Victoria Kennedy, Mark P. Krebs, Jürgen Κ. Naggert, Patsy Nishina
This paper creates a mouse model with the ARMS2A69S variant to study AMD, finding it causes mitochondrial dysfunction and AMD-like phenotypes.
bioRxiv · Oct 5, 2026 · PreprintGenetics