Author

Paul Shapiro

University of Maryland, Baltimore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander D. MacKerelliD· 1 shared Alison J. ScottiD· 1 shared Gaurav Kumar· 1 shared Lauren BaraccoiD· 1 shared Louis J. TayloriD· 1 shared Matthew B. FriemaniD· 1 shared Stuart M. WestoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Alexander D. MacKerellORCID

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1 paper

Recent·Most cited

The mammalian SKI complex is a broad-spectrum antiviral drug target that upregulates cellular cholesterol to inhibit viral replication

Stuart M. Weston, Lauren Baracco, Louis J. Taylor, Alison J. Scott, Gaurav Kumar, Paul Shapiro, Alexander D. MacKerell, Matthew B. Frieman

This paper identifies the SKI complex as a broad-spectrum antiviral target, showing that UMB18 increases cellular cholesterol via the mevalonate pathway to inhibit viral replication.

Journal of Virology · Sep 10, 2025Peer-reviewedMicrobiology