MicrobiologybioRxivPreprint
Allergic airway inflammation protects against SARS-CoV-2 and MERS-CoV disease but promotes fatal SARS-CoV-1 immunopathology
Jeremy Ardanuy, Grace Garrett, Carly Dillen…·Matthew B. Frieman
DOI 10.64898/2026.09.02.748812
Author
Louis J. Taylor
University of Maryland, BaltimoreORCID 0000-0002-6993-5838Unclaimed ORCID profile · follow to get notified of new preprints
Additional preprints under this name without ORCID
Biology Disciplines
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2019-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 17 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- ImmunologybioRxivPreprint
A phage display library to dissect antibody responses to human coronavirus spike proteins
Louis J. Taylor, Thiagarajan Venkataraman, Matthew B. Frieman
The paper develops a phage display library, C-Spike, to profile antibody responses to coronavirus spike proteins and identifies binding motifs using alanine-scanned peptides.
DOI 10.64898/2026.06.04.730002 - MicrobiologyJournal of VirologyPeer-reviewed
The mammalian SKI complex is a broad-spectrum antiviral drug target that upregulates cellular cholesterol to inhibit viral replication
Stuart M. Weston, Lauren Baracco, Louis J. Taylor…·Matthew B. Frieman
This paper identifies the SKI complex as a broad-spectrum antiviral target, showing that UMB18 increases cellular cholesterol via the mevalonate pathway to inhibit viral replication.
1 citation - MicrobiologybioRxiv
SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression
Marisa E. McGrath, Yong Xue, Louis Taylor…·Matthew B. Frieman
This study shows that SARS-CoV-2 ORF8 protein modulates lung inflammation and disease severity in mice by affecting macrophage infiltration and function.
DOI 10.1371/journal.ppat.1011669 - BioinformaticsMicrobiomePeer-reviewed
Sunbeam: an extensible pipeline for analyzing metagenomic sequencing experiments
Erik Clarke, Louis J. Taylor, Chunyu Zhao…·Kyle L. Bittinger
Sunbeam is a modular pipeline for metagenomic analysis that standardizes preprocessing and removes low-complexity reads, enabling reproducible and extensible workflows.
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