MeCP2 is Necessary in Cerebellar Purkinje Cells for Precise Network Dynamics During Associative Motor Learning
Jenny Shen, Peter Shen, Júlia Lopes Gonçalez, Mikayla Jackson, Likhitha Polepalli, Kruthika Dheeravath, Timothy Li, Abdulla Hamki, Mariam Hamki, Christian Hicks, Chang Li, Lucas D. Pozzo‐Miller, Wei Li
This study shows that MeCP2 in Purkinje cells is critical for precise timing and coordination in cerebellar learning but not for general motor behaviors.
bioRxiv · May 26, 2026 · PreprintNeuroscience