Intron retention regulates STAT2 function and predicts immunotherapy response in lung cancer
Ryan P. Englander, Mattia Brugiolo, Te-Chia Wu, Mitchell S. Kostich, Nathan K. Leclair, SungHee Park, Jacques Banchereau, Peter Yu, Andrew Salner, Romain Banchereau, Karolina Palucka, Olga Anczuków
The paper identifies intron retention in STAT2 as a regulator of immune signaling and a predictor of immunotherapy response in lung cancer.
bioRxiv · Aug 19, 2025 · PreprintImmunology