A cross ancestry genetic study of psychiatric disorders from India
Bharath Holla, Jayant Mahadevan, Suhas Ganesh, Reeteka Sud, Meghana Janardhanan, Srinivas Balachander, Nora Strom, Manuel Mattheisen, Patrick F Sullivan, Hailiang Huang, Peter Zandi, Vivek Benegal, YC Janardhan Reddy, Sanjeev Jain, cVEDA collaborators, , Biju Viswanath
This study evaluates the predictive accuracy of polygenic scores for psychiatric disorders in an Indian population using European GWAS data, finding moderate-to-high accuracy for bipolar disorder but lower for OCD and externalizing traits.
medRxiv · Apr 25, 2024 · PreprintGenetic & Genomic Medicine