Tracking cellular biomolecular condensate dynamics under proteostatic stress with middle-down phosphoproteomics
Boomathi Pandi, Dominic C. M. Ng, Peyton Schaal, Lorena Alamillo, Shaonil Binti, Edward Lau, Maggie P. Y. Lam
This study uses middle-down phosphoproteomics to analyze how protein partitioning into biomolecular condensates changes under proteostatic stress, revealing phosphorylation-dependent and independent mechanisms.
bioRxiv · Sep 23, 2026 · PreprintBiochemistry